diff --git a/.changeset/funny-bees-taste.md b/.changeset/funny-bees-taste.md
new file mode 100644
index 0000000000..a9b2d84997
--- /dev/null
+++ b/.changeset/funny-bees-taste.md
@@ -0,0 +1,5 @@
+---
+'@backstage/plugin-notifications': patch
+---
+
+The user can newly mark all unread messages as read at one click.
diff --git a/plugins/notifications/api-report.md b/plugins/notifications/api-report.md
index 9ffcf0d727..8fbd148b6d 100644
--- a/plugins/notifications/api-report.md
+++ b/plugins/notifications/api-report.md
@@ -112,6 +112,7 @@ export const NotificationsSidebarItem: (props?: {
 export const NotificationsTable: ({
   isLoading,
   notifications,
+  isUnread,
   onUpdate,
   setContainsText,
   onPageChange,
@@ -127,6 +128,7 @@ export type NotificationsTableProps = Pick<
   'onPageChange' | 'onRowsPerPageChange' | 'page' | 'totalCount'
 > & {
   isLoading?: boolean;
+  isUnread: boolean;
   notifications?: Notification_2[];
   onUpdate: () => void;
   setContainsText: (search: string) => void;
diff --git a/plugins/notifications/src/components/NotificationsPage/NotificationsPage.tsx b/plugins/notifications/src/components/NotificationsPage/NotificationsPage.tsx
index 539db4f61e..f1dd9aba5f 100644
--- a/plugins/notifications/src/components/NotificationsPage/NotificationsPage.tsx
+++ b/plugins/notifications/src/components/NotificationsPage/NotificationsPage.tsx
@@ -22,6 +22,7 @@ import {
   ResponseErrorPanel,
 } from '@backstage/core-components';
 import Grid from '@material-ui/core/Grid';
+import { ConfirmProvider } from 'material-ui-confirm';
 import { useSignal } from '@backstage/plugin-signals-react';
 
 import { NotificationsTable } from '../NotificationsTable';
@@ -32,8 +33,11 @@ import {
   SortBy,
   SortByOptions,
 } from '../NotificationsFilters';
-import { GetNotificationsOptions } from '../../api';
-import { NotificationSeverity } from '@backstage/plugin-notifications-common';
+import { GetNotificationsOptions, GetNotificationsResponse } from '../../api';
+import {
+  NotificationSeverity,
+  NotificationStatus,
+} from '@backstage/plugin-notifications-common';
 
 const ThrottleDelayMs = 2000;
 
@@ -70,7 +74,9 @@ export const NotificationsPage = (props?: NotificationsPageProps) => {
   );
   const [severity, setSeverity] = React.useState<NotificationSeverity>('low');
 
-  const { error, value, retry, loading } = useNotificationsApi(
+  const { error, value, retry, loading } = useNotificationsApi<
+    [GetNotificationsResponse, NotificationStatus]
+  >(
     api => {
       const options: GetNotificationsOptions = {
         search: containsText,
@@ -91,7 +97,7 @@ export const NotificationsPage = (props?: NotificationsPageProps) => {
         options.createdAfter = createdAfterDate;
       }
 
-      return api.getNotifications(options);
+      return Promise.all([api.getNotifications(options), api.getStatus()]);
     },
     [
       containsText,
@@ -131,6 +137,10 @@ export const NotificationsPage = (props?: NotificationsPageProps) => {
     return <ResponseErrorPanel error={error} />;
   }
 
+  const notifications = value?.[0]?.notifications;
+  const totalCount = value?.[0]?.totalCount;
+  const isUnread = !!value?.[1]?.unread;
+
   return (
     <PageWithHeader
       title={title}
@@ -141,35 +151,38 @@ export const NotificationsPage = (props?: NotificationsPageProps) => {
       typeLink={typeLink}
     >
       <Content>
-        <Grid container>
-          <Grid item xs={2}>
-            <NotificationsFilters
-              unreadOnly={unreadOnly}
-              onUnreadOnlyChanged={setUnreadOnly}
-              createdAfter={createdAfter}
-              onCreatedAfterChanged={setCreatedAfter}
-              onSortingChanged={setSorting}
-              sorting={sorting}
-              saved={saved}
-              onSavedChanged={setSaved}
-              severity={severity}
-              onSeverityChanged={setSeverity}
-            />
+        <ConfirmProvider>
+          <Grid container>
+            <Grid item xs={2}>
+              <NotificationsFilters
+                unreadOnly={unreadOnly}
+                onUnreadOnlyChanged={setUnreadOnly}
+                createdAfter={createdAfter}
+                onCreatedAfterChanged={setCreatedAfter}
+                onSortingChanged={setSorting}
+                sorting={sorting}
+                saved={saved}
+                onSavedChanged={setSaved}
+                severity={severity}
+                onSeverityChanged={setSeverity}
+              />
+            </Grid>
+            <Grid item xs={10}>
+              <NotificationsTable
+                isLoading={loading}
+                isUnread={isUnread}
+                notifications={notifications}
+                onUpdate={onUpdate}
+                setContainsText={setContainsText}
+                onPageChange={setPageNumber}
+                onRowsPerPageChange={setPageSize}
+                page={pageNumber}
+                pageSize={pageSize}
+                totalCount={totalCount}
+              />
+            </Grid>
           </Grid>
-          <Grid item xs={10}>
-            <NotificationsTable
-              isLoading={loading}
-              notifications={value?.notifications}
-              onUpdate={onUpdate}
-              setContainsText={setContainsText}
-              onPageChange={setPageNumber}
-              onRowsPerPageChange={setPageSize}
-              page={pageNumber}
-              pageSize={pageSize}
-              totalCount={value?.totalCount}
-            />
-          </Grid>
-        </Grid>
+        </ConfirmProvider>
       </Content>
     </PageWithHeader>
   );
diff --git a/plugins/notifications/src/components/NotificationsTable/BulkActions.tsx b/plugins/notifications/src/components/NotificationsTable/BulkActions.tsx
index 034da7c93c..40e2f5c8bb 100644
--- a/plugins/notifications/src/components/NotificationsTable/BulkActions.tsx
+++ b/plugins/notifications/src/components/NotificationsTable/BulkActions.tsx
@@ -22,17 +22,22 @@ import MarkAsUnreadIcon from '@material-ui/icons/Markunread' /* TODO: use Drafts
 import MarkAsReadIcon from '@material-ui/icons/CheckCircle';
 import MarkAsUnsavedIcon from '@material-ui/icons/LabelOff' /* TODO: use BookmarkRemove and BookmarkAdd once we have mui 5 icons */;
 import MarkAsSavedIcon from '@material-ui/icons/Label';
+import MarkAllReadIcon from '@material-ui/icons/DoneAll';
 
 export const BulkActions = ({
   selectedNotifications,
   notifications,
+  isUnread,
   onSwitchReadStatus,
   onSwitchSavedStatus,
+  onMarkAllRead,
 }: {
   selectedNotifications: Set<Notification['id']>;
   notifications: Notification[];
+  isUnread?: boolean;
   onSwitchReadStatus: (ids: Notification['id'][], newStatus: boolean) => void;
   onSwitchSavedStatus: (ids: Notification['id'][], newStatus: boolean) => void;
+  onMarkAllRead?: () => void;
 }) => {
   const isDisabled = selectedNotifications.size === 0;
   const bulkNotifications = notifications.filter(notification =>
@@ -58,7 +63,22 @@ export const BulkActions = ({
 
   return (
     <Grid container wrap="nowrap">
-      <Grid item>
+      <Grid item xs={3}>
+        {onMarkAllRead ? (
+          <Tooltip title="Mark all read">
+            <div>
+              {/* The <div> here is a workaround for the Tooltip which does not work for a "disabled" child */}
+              <IconButton disabled={!isUnread} onClick={onMarkAllRead}>
+                <MarkAllReadIcon aria-label={markAsSavedText} />
+              </IconButton>
+            </div>
+          </Tooltip>
+        ) : (
+          <div />
+        )}
+      </Grid>
+
+      <Grid item xs={3}>
         <Tooltip title={markAsSavedText}>
           <div>
             {/* The <div> here is a workaround for the Tooltip which does not work for a "disabled" child */}
@@ -74,7 +94,7 @@ export const BulkActions = ({
         </Tooltip>
       </Grid>
 
-      <Grid item>
+      <Grid item xs={3}>
         <Tooltip title={markAsReadText}>
           <div>
             <IconButton
diff --git a/plugins/notifications/src/components/NotificationsTable/NotificationsTable.tsx b/plugins/notifications/src/components/NotificationsTable/NotificationsTable.tsx
index f1d6e58b51..f8091a021f 100644
--- a/plugins/notifications/src/components/NotificationsTable/NotificationsTable.tsx
+++ b/plugins/notifications/src/components/NotificationsTable/NotificationsTable.tsx
@@ -23,9 +23,8 @@ import CheckBox from '@material-ui/core/Checkbox';
 import Typography from '@material-ui/core/Typography';
 import { makeStyles } from '@material-ui/core/styles';
 import { Notification } from '@backstage/plugin-notifications-common';
-
-import { notificationsApiRef } from '../../api';
-import { useApi } from '@backstage/core-plugin-api';
+import { useConfirm } from 'material-ui-confirm';
+import { alertApiRef, useApi } from '@backstage/core-plugin-api';
 import {
   Link,
   Table,
@@ -33,6 +32,8 @@ import {
   TableColumn,
 } from '@backstage/core-components';
 
+import { notificationsApiRef } from '../../api';
+
 import { SeverityIcon } from './SeverityIcon';
 import { SelectAll } from './SelectAll';
 import { BulkActions } from './BulkActions';
@@ -55,6 +56,7 @@ export type NotificationsTableProps = Pick<
   'onPageChange' | 'onRowsPerPageChange' | 'page' | 'totalCount'
 > & {
   isLoading?: boolean;
+  isUnread: boolean;
   notifications?: Notification[];
   onUpdate: () => void;
   setContainsText: (search: string) => void;
@@ -65,6 +67,7 @@ export type NotificationsTableProps = Pick<
 export const NotificationsTable = ({
   isLoading,
   notifications = [],
+  isUnread,
   onUpdate,
   setContainsText,
   onPageChange,
@@ -75,6 +78,9 @@ export const NotificationsTable = ({
 }: NotificationsTableProps) => {
   const classes = useStyles();
   const notificationsApi = useApi(notificationsApiRef);
+  const alertApi = useApi(alertApiRef);
+  const confirm = useConfirm();
+
   const [selectedNotifications, setSelectedNotifications] = React.useState(
     new Set<Notification['id']>(),
   );
@@ -117,6 +123,39 @@ export const NotificationsTable = ({
     [notificationsApi, onUpdate],
   );
 
+  const onMarkAllRead = React.useCallback(() => {
+    confirm({
+      title: 'Are you sure?',
+      description: (
+        <>
+          Mark <b>all</b> notifications as <b>read</b>.
+        </>
+      ),
+      confirmationText: 'Mark All',
+    })
+      .then(async () => {
+        const ids = (
+          await notificationsApi.getNotifications({ read: false })
+        ).notifications?.map(notification => notification.id);
+
+        return notificationsApi
+          .updateNotifications({
+            ids,
+            read: true,
+          })
+          .then(onUpdate);
+      })
+      .catch(e => {
+        if (e) {
+          // if e === undefined, the Cancel button has been hit
+          alertApi.post({
+            message: 'Failed to mark all notifications as read',
+            severity: 'error',
+          });
+        }
+      });
+  }, [alertApi, confirm, notificationsApi, onUpdate]);
+
   const throttledContainsTextHandler = React.useMemo(
     () => throttle(setContainsText, ThrottleDelayMs),
     [setContainsText],
@@ -210,8 +249,10 @@ export const NotificationsTable = ({
           <BulkActions
             notifications={notifications}
             selectedNotifications={selectedNotifications}
+            isUnread={isUnread}
             onSwitchReadStatus={onSwitchReadStatus}
             onSwitchSavedStatus={onSwitchSavedStatus}
+            onMarkAllRead={onMarkAllRead}
           />
         ),
         render: (notification: Notification) => (
@@ -220,6 +261,7 @@ export const NotificationsTable = ({
             selectedNotifications={new Set([notification.id])}
             onSwitchReadStatus={onSwitchReadStatus}
             onSwitchSavedStatus={onSwitchSavedStatus}
+            //
           />
         ),
       },
@@ -227,8 +269,10 @@ export const NotificationsTable = ({
     [
       selectedNotifications,
       notifications,
+      isUnread,
       onSwitchReadStatus,
       onSwitchSavedStatus,
+      onMarkAllRead,
       onNotificationsSelectChange,
       classes.severityItem,
       classes.description,